Announcement PDF RNS Number : 4382S Fusion Antibodies PLC 24 July 2025 24 July 2025 Fusion Antibodies plc ("Fusion"or the "Company") Issue Notification: US Patent Update Fusion Antibodies plc (AIM: FAB), specialists in pre-clinical antibody discovery, engineering and supply for both therapeutic drug and diagnostic applications, announces that the United States Patent and Trademark Office (the "U.S. Patent Office") has published a patent issue notification (the "Issue Notification") in respect of the Company's patent application no. 17/287,441 (the "Patent Application"). A patent issue notification is a document informing an applicant that their patent application has been approved and is scheduled to be granted. The Issue Notification indicates that the patent will be granted on 5 August 2025. The Patent Application, entitled "Antibody Library and Method", concerns the library of antibodies that is currently screened within Fusion's OptiMAL® platform, as well as the method for the design of additional libraries. This is key to Fusion's offering to provide "Opti" designed libraries for a range of applications including Antibody Discovery, Affinity Maturation, and Sequence Optimisation. Further patent applications and examination processes are continuing in several other territories worldwide including Europe, China and Japan. Adrian Kinkaid, CEO of Fusion, said:"This news takes us another step forward in gaining patent protection for our Opti discovery platforms including OptiMAL®. Whilst the patent itself has not yet granted, we are excited to have taken a further step toward this important milestone which we believe would represent significant value creation for the business." Navigate to our Interactive Investor hub here:https://investorhub.fusionantibodies.com/. Engage with us by asking questions, watching video summaries and seeing what other shareholders have to say. Enquiries: Fusion Antibodies plc Adrian Kinkaid, Chief Executive Officer Stephen Smyth, Chief Financial Officer www.fusionantibodies.com Via Walbrook PR Allenby Capital Limited James Reeve/Vivek Bhardwaj (Corporate Finance) Tony Quirke/Joscelin Pinnington (Sales and Corporate Broking) Tel: +44 (0)20 3328 5656 Shard Capital Partners LLP Damon Heath (Joint Broker) Walbrook PR Anna Dunphy Investor Hub We encourage all investors to share questions hubhttps://investorhub.fusionantibodies.com/link/Pbnn4P Tel: +44 (0)207 186 9952 Tel: +44 (0)20 7933 or fusion@walbrookpr.com Mob: +44 (0)7876 741 001 on this announcement 8780 via our investor About Fusion Antibodies plc Fusion is a Belfast based contract research organisation ("CRO") providing a range of antibody engineering services for the development of antibodies for both therapeutic drug and diagnostic applications. The Company's ordinary shares were admitted to trading on AIM on 18 December 2017. Fusion provides a broad range of services in antibody generation, development, production, characterisation and optimisation. These services include antigen expression, antibody production, purification and sequencing, antibody humanisation using Fusion's proprietary CDRx TM platform and the production of antibody generating stable cell lines to provide material for use in clinical trials. Since 2012, the Company has successfully sequenced and/or expressed over 750 antibodies and successfully completed over 250 humanisation projects and has an international, blue-chip client base, which has included eight of the top 10 global pharmaceutical companies by revenue. The Company was established in 2001 as a spin out from Queen's University Belfast. The Company's mission is to enable pharmaceutical and diagnostic companies to develop innovative products in a timely and cost-effective manner for the benefit of the global healthcare industry. Fusion Antibodies provides a broad range of services in antibody generation, development, production, characterisation and optimisation. Fusion Antibodies growth strategy is based on combining the latest technological advances with cutting edge science to deliver new platforms that will enable Pharma and Biotech companies get to the clinic faster, with the optimal drug candidate and ultimately speed up the drug development process. This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com. 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